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1.
Saudi Med J ; 42(12): 1341-1352, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1547838

ABSTRACT

OBJECTIVES: To identify the self-reported vaccine-related side effects among healthcare professionals (HCPs) in the Jazan province, Saudi Arabia, and determine the associated socio-demographic factors. With the recent second and third waves of coronavirus disease -19 (COVID-19) infections worldwide, the race is not only to encourage but also to achieve mass vaccination. METHODS: A total of 397 HCPs from across Jazan province participated in an anonymous online cross-sectional survey conducted for a period of 45 days (March 30, 2021 to May 13, 2021) in Jazan province, Saudi Arabia. Data was collected using a validated 22-items self-report survey. RESULTS: For both COVID-19 vaccines, majority of reports were related to flu-like symptoms including fever, chills, headache, fatigue, tiredness, and myalgia. Statistically significant associations were observed between the severity of side effects and gender (χ2=73.32; p<0.001), type of vaccine (χ2=112.08; p<0.001), and presence of known allergies (χ2=99.69; p<0.001). Female HCPs were more likely to report any side effects compared with male HCPs (adjusted odds ratio [AOR]: 3.72; p<0.001). Furthermore, HCPs with known allergies were more likely to report any side effects than their counterparts with unknown allergies (AOR: 16.29; p<0.001). CONCLUSION: The findings of the present study would help in designing educational programs aimed at combating the misconstrued fear of vaccination and highlighting the urgent need of getting vaccinated. This study also helps in the identification of factors affecting the presence and severity of side effects.


Subject(s)
COVID-19 Vaccines , COVID-19 , Cross-Sectional Studies , Delivery of Health Care , Female , Humans , Male , SARS-CoV-2 , Saudi Arabia/epidemiology , Vaccination
2.
Drug Discov Ther ; 14(2): 67-72, 2020 May 06.
Article in English | MEDLINE | ID: covidwho-116944

ABSTRACT

The virus severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is currently affecting more than 200 countries and territories worldwide. It has been declared as pandemic by World Health Organization (WHO) and the whole world is suffering from corona virus disease 2019 (COVID-19). Currently, no treatment for SARS-CoV-2 are approved because of lack of evidence, but a number of clinical trials are in process and we are expecting fruitful results very soon. This review focuses on various approaches of treatment and few of the most recent clinical trials carried out in this field.


Subject(s)
Antiviral Agents/therapeutic use , Coronavirus Infections/therapy , Pneumonia, Viral/therapy , Adenosine Monophosphate/analogs & derivatives , Adenosine Monophosphate/therapeutic use , Alanine/analogs & derivatives , Alanine/therapeutic use , Amides/therapeutic use , Antibodies, Monoclonal, Humanized/therapeutic use , Betacoronavirus , COVID-19 , Chloroquine/therapeutic use , Clinical Trials as Topic , Coronavirus Infections/drug therapy , Darunavir/therapeutic use , Drug Combinations , Humans , Hydroxychloroquine/therapeutic use , Immunization, Passive , Indoles/therapeutic use , Interferon-alpha/therapeutic use , Interferon-beta/therapeutic use , Lopinavir/therapeutic use , Pandemics , Pyrazines/therapeutic use , Ritonavir/therapeutic use , SARS-CoV-2 , COVID-19 Drug Treatment , COVID-19 Serotherapy
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